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Cipro - Ciprofloxacin, this antibiotic contributes to the appearance of multiple changes in the cellular compounds of the infection, which leads to the rapid death of microbial cells.

Active Ingredient: Ciprofloxacin

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What is Cipro

Cipro is used in the treatment of infectious diseases that are sensitive to it: respiratory tract diseases (upper section), organs of the excretory system and abdominal cavity, ODA, dermis and pancreas, ENT organs. Cipro showed high efficiency in the prevention and treatment of postoperative infections, bacterial complications of immunodeficiency states in neutropenia and other immunosuppressive disorders.

Method of application and dosage Cipro

Most often, adults are prescribed from 250 mg to 500mg Cipro in two doses per day. Sometimes a daily dosage of 1.5 g, divided into 2 doses, is acceptable. To avoid crystalluria, the drug should be washed down with plenty of water.

For the treatment of mild infections of the urinary system, 250mg of the drug are used twice a day, for moderate diseases, usually 500mg of Cipro is prescribed, in severe cases, the above dosage is increased to 750mg twice a day.

Treatment of uncomplicated gonorrhea requires the appointment of 250mg once.

Bone and joint infections are treated on average 500-750mg twice a day.

Moderate respiratory and gastrointestinal infectious processes are treated by prescribing 250-500mg of the drug twice for knocking.

The severity of the pathological process, the degree of clinical response and the results of laboratory tests determine the duration of Cipro therapy. It is continued for another 2-3 days after the elimination of the fever.

In people with renal dysfunction, correction of the drug is required. When creatinine clearance is more than 50ml min, the amount of drug taken remains the same as for healthy adults. If creatinine clearance is in the range of 30 to 50ml/min, 250 to 500mg of Cipro is used twice a day. In severe cases, with creatinine clearance from 4 to 30ml min, this amount of the drug is prescribed with an interval of 18 hours.

With parenteral administration of the substance, drip infusion is used, with a single dose of it from 100 to 400mg intravenously twice a day. In this case, the therapy lasts 7-10 days.

Infections of the dermis, subcutaneous fat, bones and joints: 200-400mg of Cipro is administered twice a day. In the treatment of intraperitoneal infections, you need to take up to 400mg twice intravenously per day. With a single injection of 200mg, the duration of the infusion lasts 30 minutes, with the introduction of 400mg for an hour.

Cipro side effects

In general, Cipro has good tolerance.

Dizziness, cranialgia, excessive fatigue, peripheral tremor, paresthesia in the extremities can rarely be observed. Some individuals have reported excessive sweating, subjective flushing, gait disturbance and depressive syndrome when taking the antibiotic.

In the gastrointestinal tract, Cipro was associated with the appearance of dry mouth, nausea, discomfort in the abdomen and loose stools, flatulence. A rather rare complication of ciprobay therapy was acute toxic damage to hepatocytes with an increase in the activity of liver enzymes in laboratory tests.

From the side of the cardiovascular system, some patients noted arterial hypertension and arrhythmias, more often tachycardia.

Among the allergic phenomena associated with taking Cipro, there are allergic urticaria with pruritus, angioedema, and in severe cases, Stevens-Jones and Lyell syndromes, anaphylactic shock. Some patients noted a petechial rash on the skin.


Cipro is not used in people with revealed excessive sensitivity to quinolone drugs.

The drug is contraindicated in women during gestation and breastfeeding, in children under 12 years of age.

Cipro is not used in people with a history of postquinolone tenosynovitis.

Cipro overdose

When taking excess amounts of Cipro in some patients, reversible toxic damage to the kidneys was noted.

In addition to the treatment of overdose status of Cipro (detoxification and symptomatic therapy), monitoring of renal functions, control of diuresis, with predominant acidification of urine and the administration of antacids that inhibit the absorption of ciprofloxacin, are recommended.

Peritoneal dialysis and its other types are ineffective in case of an overdose of antibiotics. With their help, only a tenth of the administered ciprofloxacin is excreted.

Cipro does not have a specific antidote.